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prism snapshot multiplex kit  (Thermo Fisher)


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    Structured Review

    Thermo Fisher prism snapshot multiplex kit
    Prism Snapshot Multiplex Kit, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prism+snapshot+multiplex+kits/pm40564659-69-12-16
    Average 90 stars, based on 1 article reviews
    prism snapshot multiplex kit - by Bioz Stars, 2026-10
    90/100 stars

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    Related Articles

    Primer Extension Assay:

    Article Title: Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves.
    Article Snippet: Purpose NAD(P)H dehydrogenase, encoded by NAD(P)H quinone oxidoreductase 1 (NQO1), is an enzyme that catalyzes the reduction of quinones, including vitamin K. Given its potential role in vitamin K metabolism, this study aimed to investigate the effects of NQO1 polymorphisms on stable warfarin doses.. Methods We tested a possible effect of gene polymorphisms on variability in warfarin response using 206 Korean patients with mechanical cardiac valves.. Single nucleotide polymorphisms (SNPs) of NQO1 with a minor allele frequency of at least 15 % were included.

    Article Title: Effects of Pregnane X Receptor Genetic Polymorphisms on Stable Warfarin Doses.
    Article Snippet: Objective: Pregnane X receptor (PXR) is a transcriptional regulator of many drug-metabolizing enzymes including cytochrome P450 (CYP) 2C9.. The objective of this study was to assess the possible association between PXR single-nucleotide polymorphisms (SNPs) and stable warfarin doses.. Methods: A total of 201 patients with stable warfarin doses from the EwhA-Severance Treatment (EAST) Group of Warfarin were included in this study.

    Article Title: Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
    Article Snippet: The aim of this study was to investigate the possible effects of EPHX1 and VKORC1L1 polymorphisms on variability of responses to warfarin.. Sixteen single nucleotide polymorphisms (SNPs) in 201 patients with stable warfarin doses were analyzed including genes of VKORC1, CYP2C9, CYP4F2, GGCX, EPHX1 and VKORC1L1.. Univariate analysis was conducted for the association of genotypes with stable warfarin doses.

    Article Title: Effects of KCNMB2 gene polymorphisms on ritodrine therapy outcomes in women with preterm labor
    Article Snippet: Results Patients with variant homozygotes of two SNPs (rs7624046 and rs9839376), which were in linkage disequilibrium, showed 2.06 [95% confidence interval (CI), 1.14–3.73] and 2.68 (95% CI, 1.16–6.20) times the hazard of time to delivery compared to wild-type allele carriers, respectively.. Among demographic characteristics, gestational age at start of drug therapy and modified Bishop score were significant factors for time to delivery.. Regarding safety outcomes, patients with variant homozygotes of rs7625907 had fewer ADEs compared to those with other genotypes (odds ratio, 0.32; 95% CI, 0.13–0.83).

    Article Title: Effects of SLCO1B1 and SLCO1B3 Genetic Polymorphisms on Valsartan Pharmacokinetics in Healthy Korean Volunteers
    Article Snippet: .. Genotyping of SLCO1B1 and SLCO1B3 polymorphisms was conducted with a single-base primer extension assay using ABI PRISM SNaPShot Multiplex kits (ABI, Foster City, CA, USA) according to the manufacturer’s recommendations. ..

    Article Title: Association between MKRN3 and LIN28B polymorphisms and precocious puberty
    Article Snippet: .. The genotypes of five SNPs were screened using single base primer extension assay using ABI PRISM SNaPshot Multiplex kits (ABI, Foster City, CA, USA) according to manufacturer’s protocol. ..

    Article Title: Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects
    Article Snippet: .. Genotyping of CYP3A4 , CYP3A5, and POR polymorphisms was conducted by a single‐base primer extension assay using ABI PRISM SNaPshot Multiplex Kits (ABI, Foster City, CA, USA) according to the manufacturer's recommendations. ..

    Multiplex Assay:

    Article Title: Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves.
    Article Snippet: Purpose NAD(P)H dehydrogenase, encoded by NAD(P)H quinone oxidoreductase 1 (NQO1), is an enzyme that catalyzes the reduction of quinones, including vitamin K. Given its potential role in vitamin K metabolism, this study aimed to investigate the effects of NQO1 polymorphisms on stable warfarin doses.. Methods We tested a possible effect of gene polymorphisms on variability in warfarin response using 206 Korean patients with mechanical cardiac valves.. Single nucleotide polymorphisms (SNPs) of NQO1 with a minor allele frequency of at least 15 % were included.

    Article Title: Influence of UDP-Glucuronosyltransferase Polymorphisms on Stable Warfarin Doses in Patients with Mechanical Cardiac Valves.
    Article Snippet: .. Genotyping was performed with single-base primer extension assays using ABI PRISM SNaPShot Multiplex kits (ABI, Foster City, CA, USA) according to the manufacturer’s recommendation. ..

    Article Title: Effects of Pregnane X Receptor Genetic Polymorphisms on Stable Warfarin Doses.
    Article Snippet: Objective: Pregnane X receptor (PXR) is a transcriptional regulator of many drug-metabolizing enzymes including cytochrome P450 (CYP) 2C9.. The objective of this study was to assess the possible association between PXR single-nucleotide polymorphisms (SNPs) and stable warfarin doses.. Methods: A total of 201 patients with stable warfarin doses from the EwhA-Severance Treatment (EAST) Group of Warfarin were included in this study.

    Article Title: Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
    Article Snippet: The aim of this study was to investigate the possible effects of EPHX1 and VKORC1L1 polymorphisms on variability of responses to warfarin.. Sixteen single nucleotide polymorphisms (SNPs) in 201 patients with stable warfarin doses were analyzed including genes of VKORC1, CYP2C9, CYP4F2, GGCX, EPHX1 and VKORC1L1.. Univariate analysis was conducted for the association of genotypes with stable warfarin doses.

    Article Title: Effects of KCNMB2 gene polymorphisms on ritodrine therapy outcomes in women with preterm labor
    Article Snippet: Results Patients with variant homozygotes of two SNPs (rs7624046 and rs9839376), which were in linkage disequilibrium, showed 2.06 [95% confidence interval (CI), 1.14–3.73] and 2.68 (95% CI, 1.16–6.20) times the hazard of time to delivery compared to wild-type allele carriers, respectively.. Among demographic characteristics, gestational age at start of drug therapy and modified Bishop score were significant factors for time to delivery.. Regarding safety outcomes, patients with variant homozygotes of rs7625907 had fewer ADEs compared to those with other genotypes (odds ratio, 0.32; 95% CI, 0.13–0.83).

    Article Title: Effects of SLCO1B1 and SLCO1B3 Genetic Polymorphisms on Valsartan Pharmacokinetics in Healthy Korean Volunteers
    Article Snippet: .. Genotyping of SLCO1B1 and SLCO1B3 polymorphisms was conducted with a single-base primer extension assay using ABI PRISM SNaPShot Multiplex kits (ABI, Foster City, CA, USA) according to the manufacturer’s recommendations. ..

    Article Title: Association between MKRN3 and LIN28B polymorphisms and precocious puberty
    Article Snippet: .. The genotypes of five SNPs were screened using single base primer extension assay using ABI PRISM SNaPshot Multiplex kits (ABI, Foster City, CA, USA) according to manufacturer’s protocol. ..

    Article Title: Effects of cytochrome P450 oxidoreductase genotypes on the pharmacokinetics of amlodipine in healthy Korean subjects
    Article Snippet: .. Genotyping of CYP3A4 , CYP3A5, and POR polymorphisms was conducted by a single‐base primer extension assay using ABI PRISM SNaPshot Multiplex Kits (ABI, Foster City, CA, USA) according to the manufacturer's recommendations. ..

    Genotyping Assay:

    Article Title: Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves.
    Article Snippet: Purpose NAD(P)H dehydrogenase, encoded by NAD(P)H quinone oxidoreductase 1 (NQO1), is an enzyme that catalyzes the reduction of quinones, including vitamin K. Given its potential role in vitamin K metabolism, this study aimed to investigate the effects of NQO1 polymorphisms on stable warfarin doses.. Methods We tested a possible effect of gene polymorphisms on variability in warfarin response using 206 Korean patients with mechanical cardiac valves.. Single nucleotide polymorphisms (SNPs) of NQO1 with a minor allele frequency of at least 15 % were included.

    Article Title: Effects of Pregnane X Receptor Genetic Polymorphisms on Stable Warfarin Doses.
    Article Snippet: Objective: Pregnane X receptor (PXR) is a transcriptional regulator of many drug-metabolizing enzymes including cytochrome P450 (CYP) 2C9.. The objective of this study was to assess the possible association between PXR single-nucleotide polymorphisms (SNPs) and stable warfarin doses.. Methods: A total of 201 patients with stable warfarin doses from the EwhA-Severance Treatment (EAST) Group of Warfarin were included in this study.

    Article Title: Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
    Article Snippet: The aim of this study was to investigate the possible effects of EPHX1 and VKORC1L1 polymorphisms on variability of responses to warfarin.. Sixteen single nucleotide polymorphisms (SNPs) in 201 patients with stable warfarin doses were analyzed including genes of VKORC1, CYP2C9, CYP4F2, GGCX, EPHX1 and VKORC1L1.. Univariate analysis was conducted for the association of genotypes with stable warfarin doses.

    Real-time Polymerase Chain Reaction:

    Article Title: Effects of NAD(P)H quinone oxidoreductase 1 polymorphisms on stable warfarin doses in Korean patients with mechanical cardiac valves.
    Article Snippet: Purpose NAD(P)H dehydrogenase, encoded by NAD(P)H quinone oxidoreductase 1 (NQO1), is an enzyme that catalyzes the reduction of quinones, including vitamin K. Given its potential role in vitamin K metabolism, this study aimed to investigate the effects of NQO1 polymorphisms on stable warfarin doses.. Methods We tested a possible effect of gene polymorphisms on variability in warfarin response using 206 Korean patients with mechanical cardiac valves.. Single nucleotide polymorphisms (SNPs) of NQO1 with a minor allele frequency of at least 15 % were included.

    Article Title: Polymorphisms of vitamin K-related genes (EPHX1 and VKORC1L1) and stable warfarin doses.
    Article Snippet: The aim of this study was to investigate the possible effects of EPHX1 and VKORC1L1 polymorphisms on variability of responses to warfarin.. Sixteen single nucleotide polymorphisms (SNPs) in 201 patients with stable warfarin doses were analyzed including genes of VKORC1, CYP2C9, CYP4F2, GGCX, EPHX1 and VKORC1L1.. Univariate analysis was conducted for the association of genotypes with stable warfarin doses.

    Reverse Transcription Polymerase Chain Reaction:

    Article Title: Effects of Pregnane X Receptor Genetic Polymorphisms on Stable Warfarin Doses.
    Article Snippet: Objective: Pregnane X receptor (PXR) is a transcriptional regulator of many drug-metabolizing enzymes including cytochrome P450 (CYP) 2C9.. The objective of this study was to assess the possible association between PXR single-nucleotide polymorphisms (SNPs) and stable warfarin doses.. Methods: A total of 201 patients with stable warfarin doses from the EwhA-Severance Treatment (EAST) Group of Warfarin were included in this study.



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